Long-term outcomes of patients on the 1988 West of Scotland renal transplant waiting list

Murray, E. and McMillan, M. (2015) Long-term outcomes of patients on the 1988 West of Scotland renal transplant waiting list. Scottish Medical Journal, 60(1), pp. 32-36. (doi: 10.1177/0036933014563238) (PMID:25475974)

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Abstract

Background: The prevalent population with established renal failure continues to grow.<p></p> Method: Using the Renal Electronic Patient Record, we assess the long-term outcomes of the adult population in the West of Scotland who were awaiting kidney transplantation in 1988 (n = 219), and compare the demographics to the 2011 transplant waiting list (n = 409).<p></p> Results: Comparing the 2011 transplant waiting list, there are now more patients, but they are older, more likely to be female, and are more likely to have diabetes as a cause of renal failure. Seventy-four percent received a transplant; of these, 41% of the transplants ultimately failed and the patient returned to dialysis; 39% of patients died with a functioning graft and 20% remain alive with continuing transplant function. Life expectancy for those with renal failure was less than 60 years, significantly lower than the general population, though 29% survived for 20 years, half of these with a functioning kidney transplant and half having returned to dialysis.<p></p> Conclusion: As survival with a transplant improves, attention is required to reduce the causes of mortality, in particular cardiovascular disease, and malignancy and infection associated with immunosuppression.<p></p>

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:McMillan, Dr Margaret and Murray, Dr Eleanor
Authors: Murray, E., and McMillan, M.
College/School:College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health
College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
Journal Name:Scottish Medical Journal
Publisher:SAGE Publications
ISSN:0036-9330
ISSN (Online):2045-6441

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