Heydari, E., Thompson, D., Graham, D., Cooper, J. M. and Clark, A. W. (2015) An Engineered Nano-Plasmonic Biosensing Surface for Colorimetric and SERS Detection of DNA-Hybridization Events. In: Plasmonics in Biology and Medicine XII, San Francisco CA, USA, 7-8 Feb 2015, 93400O. (doi: 10.1117/12.2076915)
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Abstract
We report a versatile nanophotonic biosensing platform that enables both colorimetric detection and enhanced Raman spectroscopy detection of molecular binding events. Through the integration of electron-beam lithography, dip-pennanolithography and molecular self-assembly, we demonstrate plasmonic nanostructures which change geometry and plasmonic properties in response to molecularly-mediated nanoparticle binding events. These biologically-active nanostructured surfaces hold considerable potential for use as multiplexed sensor platforms for point-of-care diagnostics, and as scaffolds for a new generation of molecularly dynamic metamaterials. © (2015) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
| Item Type: | Conference Proceedings |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Clark, Professor Alasdair and Cooper, Professor Jonathan and Heydari, Dr Esmaeil |
| Authors: | Heydari, E., Thompson, D., Graham, D., Cooper, J. M., and Clark, A. W. |
| College/School: | College of Science and Engineering > School of Engineering > Biomedical Engineering |
| ISSN: | 0277-786X |
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