An Engineered Nano-Plasmonic Biosensing Surface for Colorimetric and SERS Detection of DNA-Hybridization Events

Heydari, E., Thompson, D., Graham, D., Cooper, J. M. and Clark, A. W. (2015) An Engineered Nano-Plasmonic Biosensing Surface for Colorimetric and SERS Detection of DNA-Hybridization Events. In: Plasmonics in Biology and Medicine XII, San Francisco CA, USA, 7-8 Feb 2015, 93400O. (doi:10.1117/12.2076915)

Full text not currently available from Enlighten.

Abstract

We report a versatile nanophotonic biosensing platform that enables both colorimetric detection and enhanced Raman spectroscopy detection of molecular binding events. Through the integration of electron-beam lithography, dip-pennanolithography and molecular self-assembly, we demonstrate plasmonic nanostructures which change geometry and plasmonic properties in response to molecularly-mediated nanoparticle binding events. These biologically-active nanostructured surfaces hold considerable potential for use as multiplexed sensor platforms for point-of-care diagnostics, and as scaffolds for a new generation of molecularly dynamic metamaterials. © (2015) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.

Item Type:Conference Proceedings
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Clark, Dr Alasdair and Cooper, Professor Jonathan and Heydari, Dr Esmaeil
Authors: Heydari, E., Thompson, D., Graham, D., Cooper, J. M., and Clark, A. W.
College/School:College of Science and Engineering > School of Engineering > Biomedical Engineering
ISSN:0277-786X

University Staff: Request a correction | Enlighten Editors: Update this record

Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
561421Plasmon Enhanced Pyroelectric Nanoscale Trapping and SensingAlasdair ClarkThe Royal Academy of Engineering (RAE)10216/103ENG - BIOMEDICAL ENGINEERING