Neužil, P., Campos, C.D.M., Wong, C.C., Soon, J.B.W., Reboud, J. and Manz, A. (2014) From chip-in-a-lab to lab-on-a-chip: towards a single handheld electronic system for multiple application-specific lab-on-a-chip (ASLOC). Lab on a Chip, 14(13), pp. 2168-2176. (doi: 10.1039/c4lc00310a)
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Abstract
We present a portable, battery-operated and application-specific lab-on-a-chip (ASLOC) system that can be easily configured for a wide range of lab-on-a-chip applications. It is based on multiplexed electrical current detection that serves as the sensing system. We demonstrate different configurations to perform most detection schemes currently in use in LOC systems, including some of the most advanced such as nanowire-based biosensing, surface plasmon resonance sensing, electrochemical detection and real-time PCR. The complete system is controlled by a single chip and the collected information is stored in situ, with the option of transferring the data to an external display by using a USB interface. In addition to providing a framework for truly portable real-life developments of LOC systems, we envisage that this system will have a significant impact on education, especially since it can easily demonstrate the benefits of integrated microanalytical systems.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Reboud, Professor Julien |
| Authors: | Neužil, P., Campos, C.D.M., Wong, C.C., Soon, J.B.W., Reboud, J., and Manz, A. |
| College/School: | College of Science and Engineering > School of Engineering > Biomedical Engineering |
| Journal Name: | Lab on a Chip |
| Publisher: | Royal Society of Chemistry |
| ISSN: | 1473-0197 |
| ISSN (Online): | 1473-0189 |
| Copyright Holders: | Copyright © 2014 The Royal Society of Chemistry |
| First Published: | First published in Lab on a Chip 14(13):2168-2176 |
| Publisher Policy: | Reproduced under a Creative Commons License |
| Related URLs: |
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