Xu, G., Gunson, R. N., Cooper, J. and Reboud, J. (2015) Rapid ultrasonic isothermal amplification of DNA with multiplexed melting analysis – applications in the clinical diagnosis of sexually transmitted diseases. Chemical Communications, 51(13), pp. 2589-2592. (doi: 10.1039/c4cc08389j) (PMID:25569801)
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Abstract
We describe a nucleic acid testing (NAT) platform for infectious disease diagnostics at the point-of-care, using surface acoustic waves (SAW) to perform a multiplexed loop-mediated isothermal amplification (LAMP) test for sexually transmitted diseases. The ultrasonic actuation not only enables faster NAT reactions but also provides a route towards integrating low-cost, low-power molecular diagnostics into disposable sensors.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Cooper, Professor Jonathan and Reboud, Professor Julien and Gunson, Dr Rory |
| Authors: | Xu, G., Gunson, R. N., Cooper, J., and Reboud, J. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity College of Science and Engineering > School of Engineering > Biomedical Engineering |
| Journal Name: | Chemical Communications |
| Publisher: | R S C Publications |
| ISSN: | 1359-7345 |
| ISSN (Online): | 0009-241X |
| Published Online: | 23 December 2014 |
| Copyright Holders: | Copyright © 2015 The Royal Society of Chemistry |
| First Published: | First published in Chemical Communications 51(13):2589-2592 |
| Publisher Policy: | Reproduced under a Creative Commons License |
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