Varicella-zoster virus claims yet another painful scalp: giant cell arteritis

Kennedy, P. G.E. and Lipton, H. L. (2015) Varicella-zoster virus claims yet another painful scalp: giant cell arteritis. Neurology, 84(19), pp. 1918-1919. (doi: 10.1212/WNL.0000000000001459) (PMID:25724229)

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Giant cell arteritis (GCA), characterized pathologically by inflammation in and damage to the vessel wall of the temporal arteries (TAs), is a medical emergency due to the potential for sudden blindness and several other serious neurologic complications if untreated with corticosteroids. The diagnosis is suspected in elderly individuals with a typical history, including headache, scalp tenderness, weight loss, fatigue, jaw claudication, and raised erythrocyte sedimentation rate and C-reactive protein.1 While the characteristic histopathologic features are often detected on TA biopsy, some patients may present with a classical history of GCA but have a negative biopsy,2 indicating either a false-negative biopsy or another etiology for the symptoms.

Item Type:Articles (Editorial)
Glasgow Author(s) Enlighten ID:Kennedy, Professor Peter
Authors: Kennedy, P. G.E., and Lipton, H. L.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Neurology
Publisher:American Academy of Neurology
ISSN (Online):1526-632X

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