Short and efficient synthesis of fluorinated δ-lactams

Cogswell, T. J., Donald, C. S., Long, D.-L. and Marquez, R. (2015) Short and efficient synthesis of fluorinated δ-lactams. Organic and Biomolecular Chemistry, 13(3), pp. 717-728. (doi: 10.1039/c4ob01547a)

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The diastereoselective synthesis of fluorinated δ-lactams has been achieved through an efficient five step process. The route can tolerate a range of functionalities, and provides a quick route for the generation of new fluorinated medicinal building blocks.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Marquez, Dr Rudi and Long, Dr Deliang
Authors: Cogswell, T. J., Donald, C. S., Long, D.-L., and Marquez, R.
College/School:College of Science and Engineering > School of Chemistry
Journal Name:Organic and Biomolecular Chemistry
Publisher:Royal Society of Chemistry
ISSN (Online):1477-0539
Copyright Holders:Copyright © 2015 The Royal Society of Chemistry
First Published:First published in Organic and Biomolecular Chemistry 13(3):717-728
Publisher Policy:Reproduced under a Creative Commons License
Data DOI:/10.5517/cc12s466

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
504321New Chemistry Approaches for the Next Generation of HealthcareRudi MarquezEngineering & Physical Sciences Research Council (EPSRC)EP/H005692/1CHEM - CHEMISTRY