Kontny, E., Szczepańska, K., Kowalczewski, J., Kurowska, M. , Janicka, I., Marcinkiewicz, J. and Maśliński, W. (2000) The mechanism of taurine chloramine inhibition of cytokine (interleukin-6, interleukin-8) production by rheumatoid arthritis fibroblast-like synoviocytes. Arthritis and Rheumatism, 43(10), pp. 2169-2177.
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Abstract
Tau-Cl inhibition of IL-6 and IL-8 synthesis in FLS from RA patients results from the ability of this compound to diminish the activity of the major transcriptional regulators (NF-kappaB and AP-1), which subsequently reduces the transcription of these cytokine genes.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Kurowska-Stolarska, Professor Mariola |
Authors: | Kontny, E., Szczepańska, K., Kowalczewski, J., Kurowska, M., Janicka, I., Marcinkiewicz, J., and Maśliński, W. |
College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity |
Journal Name: | Arthritis and Rheumatism |
Publisher: | John Wiley & Sons, Inc. |
ISSN: | 0004-3591 |
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