Ziolkowska, M. et al. (2002) High levels of osteoprotegerin and soluble receptor activator of nuclear factor kappa B ligand in serum of rheumatoid arthritis patients and their normalization after anti-tumor necrosis factor alpha treatment. Arthritis and Rheumatism, 46(7), pp. 1744-1753. (doi: 10.1002/art.10388)
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Abstract
Although higher serum levels of OPG and sRANKL are present in RA patients than in healthy individuals, the ratio of OPG:sRANKL is similar. There is an age-dependent increase of OPG but not sRANKL levels in healthy subjects. Anti-TNF alpha treatment results in the normalization of elevated levels of OPG and sRANKL in RA patients.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Kurowska-Stolarska, Professor Mariola |
Authors: | Ziolkowska, M., Kurowska, M., Radzikowska, A., Luszczykiewicz, G., Wiland, P., Dziewczopolski, W., Filipowicz-Sosnowska, A., Pazdur, J., Szechinski, J., Kowalczewski, J., Rell-Bakalarska, M., and Maslinski, W. |
College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity |
Journal Name: | Arthritis and Rheumatism |
Publisher: | John Wiley & Sons, Inc. |
ISSN: | 0004-3591 |
ISSN (Online): | 2326-5205 |
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