Binary behaviour of an oxidation-responsive MRI nano contrast agent

Jeanmaire, D., Timco, G. A., Gennari, A., Sproules, S. , Williams, K. J., Winpenny, R. E.P. and Tirelli, N. (2015) Binary behaviour of an oxidation-responsive MRI nano contrast agent. Chemical Communications, 51(6), pp. 1074-1076. (doi:10.1039/C4CC08024F)

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Abstract

A new nano contrast agent has been prepared incorporating a molecular magnet in oxidation-responsive nanoparticles; this system has shown a remarkable sensitivity to hydrogen peroxide (detection down to at least 40 μM), which was used as a model reactive oxygen species. Surprisingly, the response had a binary (off/on) character, due to a non-linear cascade relation between extent of oxidation and water permeability in the particles.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Sproules, Dr Stephen
Authors: Jeanmaire, D., Timco, G. A., Gennari, A., Sproules, S., Williams, K. J., Winpenny, R. E.P., and Tirelli, N.
College/School:College of Science and Engineering > School of Chemistry
Journal Name:Chemical Communications
Journal Abbr.:Chem. Comm.
Publisher:Royal Society of Chemistry
ISSN:1359-7345
ISSN (Online):1364-548X
First Published:First published in Chemical Communications 51(6):1074-1076

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