Multitrait indices to predict worm length and number in sheep with natural, mixed predominantly Teladorsagia circumcincta infection

Mair, C., Matthews, L. , Prada J. de Cisneros, J., Stefan, T. and Stear, M. J. (2015) Multitrait indices to predict worm length and number in sheep with natural, mixed predominantly Teladorsagia circumcincta infection. Parasitology, 142(6), pp. 773-782. (doi:10.1017/S0031182014001905) (PMID:25586410) (PMCID:PMC4413790)

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Abstract

Accurately identifying resistance to gastrointestinal nematode infections requires the ability to identify animals with low and high intensities of infection. The pathogenic effects of nematodes depend upon both the length and number of worms, neither of which can be measured in live animals. Indices that predict these quantities are urgently needed. Monthly fecal egg counts, bodyweights, IgA concentrations and pepsinogen concentrations were measured on Scottish Blackface sheep naturally infected with a mixture of nematodes, predominantly Teladorsagia circumcincta. Worm number and average worm length were available on over 500 necropsied lambs. We derived predictive indices for worm length and number using linear combinations of traits measured in live animals. The correlations between the prediction values and the observed values were 0·55 for worm length and 0·51 for worm number. These indices can be used to identify the most resistance and susceptible lambs.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Stefan, Mr Thorsten and Mair, Miss Colette and Prada Jimenez de Cisneros, Dr Joaquin and Stear, Professor Michael and Matthews, Professor Louise
Authors: Mair, C., Matthews, L., Prada J. de Cisneros, J., Stefan, T., and Stear, M. J.
College/School:College of Medical Veterinary and Life Sciences > Institute of Biodiversity Animal Health and Comparative Medicine
Journal Name:Parasitology
Publisher:Cambridge University Press
ISSN:0031-1820
ISSN (Online):1469-8161
Copyright Holders:Copyright © 2015 The Authors
First Published:First published in Parasitology 142(6):773-782
Publisher Policy:Reproduced under a Creative Commons License

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
629831The influence of selective breeding on MHC diversityMichael StearBiotechnology and Biological Sciences Research Council (BBSRC)BB/L004070/1RI BIODIVERSITY ANIMAL HEALTH & COMPMED
536761Why some hosts have high parasite burdens and the implications for the design of sustainable control strategiesLouise MatthewsWellcome Trust (WELLCOME)091717/Z/10/ZRI BIODIVERSITY ANIMAL HEALTH & COMPMED